30 Soft Gelatin Capsules
  • Improves Liver Function
  • Fatty Liver Treatment
  • Hepatitis & Cirrhosis Treatment
  • Gallbladder Disorders Treatment
  • Product Name: LiverMed
  • Medicinal Form: Softgels
  • Ingredients: 700 mg Silybum marianum L. extract standardized on minimum 7.5% total silymarin as silybin A & B using HPLC method (equivalent to 140 mg in UV method), PEG, Glycerol, Gelatin
  • Dosage and directions: Three times a day, take one capsule each time, with plenty of water, preferably before meals.
  • Prohibited Usage: This product is contraindicated in cases of known allergy to plants of the Asteraceae family.
  • Use in Pregnancy and Lactation: Should not be used during pregnancy and lactation.
  •  Side Effects: Gastrointestinal problems such as diarrhea and nausea, and also allergic reactions such as pruritus and skin rash, may rarely occur following product consumption.
  •  Cautions and warnings: Do not chew, capsules should be swallowed with plenty of water. Consult your physician of pharmacist before use, if you are taking any other medication. Read the brochure before using. Keep out of reach of children.
  •  Storage: Store in the package away from light, in a cool, dry place at room temperature below 25°C.

Liver, one of the most important organs in the body, is located in the upper portion of the abdominal cavity, beneath the diaphragm. The liver plays a key role in the human body by detoxification, regulating blood clotting, producing energy, metabolizing drugs, and hundreds of other vital functions. Many different factors such as unhealthy diet, environmental issues, genetics, and side effects of various medications are among the known causes of hepatic disorder and fatty liver.

atty liver, the most common liver disease, is described as the build-up of fats in the liver that causes severe problems in the body by disturbing liver function and its enzymes. Due to the serious damage of liver diseases to general health, it is vital to manage and treat them by utilizing safe and standardized medications. In today’s medicine, some standardized natural medications are prescribed as the main treatment for various liver diseases.

LiverMed capsules, formulated by Zardband Pharmaceuticals, contain the active ingredients of Silybum marianum plant which is the best-known treatment of hepatic disorders and improvement of liver function. The liquid formulation of LiverMed capsules, also eases the absorption of its active ingredients, and increases its efficacy, making it the perfect solution to have a healthy liver.

Silymarin, generally defined as the active substance of standardized Silybum marianum extract and the main ingredient of Livermed capsules, contains a mixture of flavonilignans consisting of silybin A and silybin B, as its major active constituents, in addition to isosilybin A, isosilybin B, silychristin, isosilychristin, silydianin and others. The efficacy of silymarin in treatment of liver diseases is a result of its various mechanisms of action which are known to improve liver function or treat the diseases.

Hepatic fibrosis is known as a pathological consequence of chronic liver diseases and can result in excessive scar tissue, due to an improper wound healing process to liver injury. Silymarin, plays a crucial role in regeneration of liver tissue by increasing the formation of ribosomes, DNA synthesis, as well as stimulating factors influencing protein synthesis. It also prevents fibrosis by inhibiting the conversion of Stellate cells to myofibroblasts and helps regenerate the liver by inhibiting inflammatory processes.

An increase in production of free radicals in the liver metabolism has been implicated in a variety of liver diseases. Free radicals can damage cell membrane and also cause lipid peroxidation. Silymarin could prevent the free radical formation via inhibition of ROS production in mitochondria, the major site of ROS generation. The active ingredients of LiverMed Capsules may also collect free radicals from the intestine, and prevent lipid peroxidation via an increase in the levels of catalase and glutathione peroxidase, which are the enzymes with a fundamental role in protection against free radical attack.

Silymarin, inhibits the cyclooxygenase, leukotrienes, and the production of free radicals by activating enzymes with antioxidant activity and non-enzymatic antioxidants inside the cell. Another protective effect of LiverMed capsules, in cases of hepatotoxicity and other common liver diseases, could be the inhibition of NF-kappa B activation followed by decreasing the production of inflammatory cytokine, and regulation of cell membrane permeability.

Silymarin, by increasing the solubility and bile flow, can also reduce the risk of developing gallstones. Moreover, it can facilitate removal of stones, improve digestion and prevent indigestion via an increase in the secretion of bile into the small intestine.