Stress and anxiety, the most prevalent psychiatric disorders, are natural reactions of the human body and brain, sometimes caused by external factors and sometimes without any external reason. Stress is usually triggered by a sudden accident or tension. It can be short-term, like when there is an important decision to be made, or long-term like in times of suffering from a chronic disease. On the other hand, anxiety is defined by persistent and excessive worries that sometimes appear even without external stressors.

Stress and anxiety have harmful effects on the mental and general health of our bodies and can seriously affect the person’s thoughts, behaviors and emotions. Problems including sleep disorders, insomnia, lack of concentration, weak immune system, fatigue, muscle tension, and anger are among the negative effects of stress and anxiety. Concerning these harmful effects, appropriate management and optimal treatment of stress and anxiety are vital to our health and use of natural and herbal sedatives is one of the most effective treatments known. Lavandeep capsules, formulated by Zardband Pharmaceuticals, contain the active ingredients of Lavandula angustifolia plant, recognized for its efficacy in treatment of stress, and mood disorders such as anxiety and restlessness. It also helps improve sleep quality, which is a vital component of our well-being.

T-type calcium channels play an essential role in the functioning of the nervous system. These channels are expressed throughout the brain, especially in stress-sensitive regions. Studies have described that increased activity of T-type calcium channels can cause anxiety-related behavior. As a result, blocking the activity of these channels could reduce anxiety. Thus, T-type calcium channels could be attractive molecular drug targets. Norepinephrine is a neurotransmitter, known as a stress hormone and plays an important role in the body’s “fight-or-flight” response. Linalool, one of the main active ingredients of Lavandeep capsules, by blocking the T-type calcium channels (TTCCs), inhibits the release of the norepinephrine and leads to anxiety relief. Blocking the T-type calcium channels (TTCCs) also prevents the release of the excitatory neurotransmitter glutamate, which increases the activity of nerve fibers in the CNS, and reduces anxiety. On the other hand, linalool, a competitive antagonist of NMDA receptors, shows its sedative effects, through interfering the glutamatergic transmissions, and improves sleep.

Serotonin is a transmitter and regulator of the nervous system, which is also known as the hormone of happiness. Serotonin deficiency has been linked to both anxiety and insomnia. Thus, bringing it up to normal is an effective way to face the issue. Linalool could reduce stress and improve insomnia, by inhibiting the serotonin transmitter (SERT) and keeping the hormone at a normal level.